BIOBASE Genome TraxTM and Avadis® NGS
Strand Scientific Intelligence, Inc. and BIOBASE GmbH have joined forces to bring you one of BIOBASE’s latest biological databases - BIOBASE Genome Trax – as integrated annotations, accessible in just one click from within the RNA-Seq, DNA-Seq, and ChIP-Seq workflows in Avadis NGS. Request a quote!
Get immediate insight into the biological relevance of discovered variations
Avadis NGS gives you the tools for identifying genomic variants like SNPs, MNPs, InDels, and larger structural variations in your NGS data. Annotating these variants with the superior, human curated annotations of Genome Trax will give you immediate insight into which of these variants is already known to be involved in a disease-related pathway or located in or near a known regulatory site. This knowledge will narrow down the regions of interest to your research, saving you valuable time and effort.
We have integrated the following five annotation tracks for human data (builds hg18 and hg19) into Avadis NGS:
- 3,000+ regulatory sites from TRANSFAC®
- 80,000+ disease linked mutations from HGMD® Professional
- 600,000+ ChIP-Seq fragments with best binding site predictions
- Post Translational Modifications (PTMs)
- Transcription Start Sites (TSSs)
They can be downloaded from the Strand Server via the Annotations Manager in Avadis NGS. After that, any region list can be annotated with one or several of the Genome Trax annotations at the same time with the Annotate with Genome Trax operation in the Utilities section of the experiment workflow. Genome Trax annotations are updated quarterly by the BIOBASE experts and we implement these updates in line with their schedule.
You will also be able to try Genome Trax in Avadis NGS for yourself when you request a free Avadis NGS evaluation, giving you access to a fully-functional version of Avadis NGS that includes a demo project containing Genome Trax annotations for chromosome 21 (human, build hg18).
